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Spindle cell sarcoma in dogs2/22/2023 ![]() ![]() Low-grade spindle cell sarcomas located at or distal to the elbow and stifle joints can be excised without need for wide or radical surgery. Marginal surgical excision without adjuvant treatment of low-grade soft tissue spindle cell sarcoma of the extremities results in a low local recurrence rate. There were no significant differences among survival functions stratified by histologic margins. Median DFI and survival time were not reached, because <50% of dogs died of disease-related events. Local recurrence and metastatic rates were 10.8% and 0%, respectively. Follow-up after surgery occurred from 210 to 2202 days (minimum, 180 days). Histopathologic margins were dirty (12 dogs), clean but close (12), and clean (11). Medical records were reviewed and dogs that had marginal surgical resection of low-grade soft tissue spindle cell sarcoma at or distal to elbow and stifle were included. © 2015 American College of Veterinary Radiology.To evaluate recurrence rate and disease-free interval (DFI) of dogs with low-grade soft tissue spindle cell sarcoma of the extremities treated by marginal excision.ĭogs (n=35) with soft tissue low-grade spindle cell sarcoma. ![]() The high frequency of abdominal effusion with GIST's was of unknown etiology could possibly have been due to septic peritonitis.Ĭanine cecum gastrointestinal stromal tumor ultrasound. Similar to previous studies, GISTs appeared to be the most common spindle cell tumor associated with the cecum in our sample of dogs. Besides location, there were no unique ultrasound features of GISTs that would allow distinction from other gastrointestinal spindle cell tumors. There was overlap between the anatomical locations of all tumors types with the exception of the cecum where all eight tumors identified were GISTs. Gastrointestinal stromal tumors were significantly more likely to be associated (P < 0.03) with abdominal effusion than other tumor types. Tumor types included 19 GISTs, eight leiomyosarcomas, six leiomyomas, and four nonspecified sarcomas. These tumors are the result of abnormal production of these cell types in an uncontrolled manner. Ultrasonographic features recorded examined included mass echogenicity, homogeneity, presence of cavitation, layer of origin, bowel wall symmetry, and loss of wall layering, location, size, vascularity, and evidence of perforation or ulceration. Soft tissue sarcomas are a broad category of tumors including those that arise from the connective, muscle, or nervous tissues in dogs and cats. Immunohistochemistry staining was performed for retrieved tissue samples to further differentiate the tumor type and each sample was interpreted by a single veterinary pathologist. Thirty-seven dogs with an ultrasonographically visible gastrointestinal mass and a histopathologic diagnosis of spindle cell neoplasia were examined. The objective of this retrospective, cross-sectional study was to describe ultrasonographic features of canine GISTs compared with other spindle cell tumors. To our knowledge, no imaging features have been described in immunostochemically confirmed canine GISTs. Canine gastrointestinal stromal tumors (GISTs) are a recent subtype of gastrointestinal spindle cell tumor recognized with the increasing use of immunohistochemistry. ![]()
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